Working with Us
Challenging. Meaningful. Life-changing. Those aren’t words that are usually associated with a job. But working at Bristol Myers Squibb is anything but usual. Here, uniquely interesting work happens every day, in every department. From optimizing a production line to the latest breakthroughs in cell therapy, this is work that transforms the lives of patients, and the careers of those who do it. You’ll get the chance to grow and thrive through opportunities uncommon in scale and scope, alongside high-achieving teams rich in diversity. Take your career farther than you thought possible.
Bristol Myers Squibb recognizes the importance of balance and flexibility in our work environment. We offer a wide variety of competitive benefits, services and programs that provide our employees with the resources to pursue their goals, both at work and in their personal lives. Read more: careers.bms.com/working-with-us.
Senior Scientist, Method Development (Regulated Bioanalysis)
Please Note: The position will be responsible for evaluating and implementing bioanalytical methods in the development stage.
At Bristol Myers Squibb, we are inspired by a single vision – transforming patients’ lives through science. In oncology, hematology, immunology and cardiovascular disease – and one of the most diverse and promising pipelines in the industry – each of our passionate colleagues contribute to innovations that drive meaningful change. We bring a human touch to every treatment we pioneer. Join us and make a difference.
The Regulated Bioanalytical function within Precision Medicine, Bioanalytical & Translational Sciences is a centralized function for testing biological samples for Pharmacokinetics (PK), Biomarkers, and Immunogenicity assessments. The responsibilities of the groups include providing bioanalytical leadership on BMS drug development teams via scientific/technical expertise and strategic input; overseeing and/or performing assay development/validation, and sample analysis; supporting discovery studies for biotherapeutics and regulated and non-regulated bioanalysis for toxicology and clinical studies; and preparing appropriate documentation and/or interacting with health authorities on the BA portion of regulatory filings. The BA groups utilize both internal resources and external strategic partners to ensure on-time delivery of BA data to enable key decisions for the organization.
The position will be responsible for evaluating and implementing bioanalytical methods in the development stage. The individual will provide leadership on the BA/biomarker method development, validation, and study support of development compounds from various modalities (small molecule, large molecule therapeutics, etc.) mainly using LC-MS technology. In addition, the candidate will play a critical role as an expert in the evaluation advanced laboratory equipment. There are also development opportunities to act as a BA or biomarker lead on cross-functional study teams, and work with them to address bioanalytical and biomarker-related issues.
- Evaluate and apply novel techniques or approaches to address challenging bioanalytical and biomarker issues.
- Conduct in-house bioanalytical and biomarker support for development programs with tandem mass spectrometry-based method development, validation, sample analysis, data interpretation, to report preparation in a regulated laboratory.
- Be the technical expert on sample cleanup, chromatography, mass spectrometric instrumentation, stability, and other method related issues.
- Interact with bioanalytical CROs to address method related issues and provide leadership for the knowledge transfer of novel technologies.
- Keep management apprised of project status and current scientific trends using written and oral summaries, as well as presentations.
Basic Qualifications:
- Ph.D. or equivalent advanced degree in the Life Sciences
2+ of academic and / or industry experience
- Ph.D. or equivalent advanced degree in the Life Sciences
4+ of academic and / or industry experience
- Preferred candidate will have a degree in chemistry, biochemistry, biology or related fields, plus relevant drug development experience at either a pharmaceutical company or a bioanalytical & biomarker CRO.
- A good understanding of bioanalysis & biomarker and their roles in drug development, including method development, validation, study support, and impact of quality bioanalytical/biomarker data to PK/PD correlation.
- Strong LC-MS/MS skills with separation and quantitation (or identification) of small (e.g. chiral assays) or large molecule therapeutics (e.g. hybrid assays for ADCs) and biomarkers (e.g. small molecule/protein assays) in biological matrices. A strong foundation and experience in using, maintaining, and trouble-shooting mass spectrometers is preferred.
- Experiences in performing LC-MS/MS and LBA method development, qualification/validation, and study sample analysis in a regulated environment to support preclinical and clinical studies with compliance.
- A proven track record of method development accomplishments in the field (thru presentations or publications).
- Good communication skills and experience in authoring and reviewing bioanalytical & biomarker assay, troubleshooting assay issues and direct junior scientist.
- Ability to multi-task and work in a collaborative team environment.
- Ability to communicate effectively in a team-based environment.
Around the world, we are passionate about making an impact on the lives of patients with serious diseases. Empowered to apply our individual talents and diverse perspectives in an inclusive culture, our shared values of passion, innovation, urgency, accountability, inclusion and integrity bring out the highest potential of each of our colleagues.
Bristol Myers Squibb recognizes the importance of balance and flexibility in our work environment. We offer a wide variety of competitive benefits, services and programs that provide our employees with the resources to pursue their goals, both at work and in their personal lives.
Physical presence at the BMS worksite or physical presence in the field is an essential job function of this role which the Company deems critical to collaboration, innovation, productivity, employee well-being and engagement, and enhances the Company culture.
#LI-ONSITE
If you come across a role that intrigues you but doesn’t perfectly line up with your resume, we encourage you to apply anyway. You could be one step away from work that will transform your life and career.
Uniquely Interesting Work, Life-changing Careers
With a single vision as inspiring as “Transforming patients’ lives through science™ ”, every BMS employee plays an integral role in work that goes far beyond ordinary. Each of us is empowered to apply our individual talents and unique perspectives in an inclusive culture, promoting diversity in clinical trials, while our shared values of passion, innovation, urgency, accountability, inclusion and integrity bring out the highest potential of each of our colleagues.
On-site Protocol
BMS has a diverse occupancy structure that determines where an employee is required to conduct their work. This structure includes site-essential, site-by-design, field-based and remote-by-design jobs. The occupancy type that you are assigned is determined by the nature and responsibilities of your role:
Site-essential roles require 100% of shifts onsite at your assigned facility. Site-by-design roles may be eligible for a hybrid work model with at least 50% onsite at your assigned facility. For these roles, onsite presence is considered an essential job function and is critical to collaboration, innovation, productivity, and a positive Company culture. For field-based and remote-by-design roles the ability to physically travel to visit customers, patients or business partners and to attend meetings on behalf of BMS as directed is an essential job function.
BMS is dedicated to ensuring that people with disabilities can excel through a transparent recruitment process, reasonable workplace accommodations/adjustments and ongoing support in their roles. Applicants can request a reasonable workplace accommodation/adjustment prior to accepting a job offer. If you require reasonable accommodations/adjustments in completing this application, or in any part of the recruitment process, direct your inquiries to adastaffingsupport@bms.com. Visit careers.bms.com/eeo-accessibility to access our complete Equal Employment Opportunity statement.
BMS cares about your well-being and the well-being of our staff, customers, patients, and communities. As a result, the Company strongly recommends that all employees be fully vaccinated for Covid-19 and keep up to date with Covid-19 boosters.
BMS will consider for employment qualified applicants with arrest and conviction records, pursuant to applicable laws in your area.
If you live in or expect to work from Los Angeles County if hired for this position, please visit this page for important additional information: https://careers.bms.com/california-residents/
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